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DTRI offers vouchers for specialty research services

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The Duke Translational Research Institute (DTRI) supports a variety of specialty technical research cores. As part of its voucher program, the DTRI offers up to $10,000 to enable Duke investigators to access these specialty core services to address specific questions in their translational research projects.

One goal of this program is to provide investigators with access to experts in these core service areas, thus expanding their ability to generate data that will support the development and submission of applications for awards through other grant funding mechanisms. The DTRI voucher is awarded to innovative research proposals that have the potential for high translational impact. The voucher does not need to be repaid.

Please review the Voucher Program RFA for more information.

Prior to applying for the voucher program, investigators should contact the appropriate specialty core to seek advice about developing a project plan. Once the plan is finalized, investigators must submit a 1-page application via the DTMI Grants Management System (https://webgrants.dtmi.duke.edu).

Specialty Cores
Core Contact

BioBanking: The DNA Bank and Tissue Repository is a biobank storage facility
that processes and stores samples while following rigorous security measures.


David Layfield
919.668.0232 bdl5@chg.duhs.duke.edu

Duke RNAi Core Facility: This facility serves as the focal point of RNAi technology development and expertise for the Duke University and Medical Center research community, and will work to advance and apply gene silencing technologies to a broad range of research programs

James Pearson
919-613-5132
james.pearson@duke.edu


Duke Image Analysis Laboratory (DIAL): This Good Clinical Practice (GCP)-compliant lab analyzes images from various modalities including x-ray, computed tomography, magnetic resonance imaging, and nuclear medicine. This lab also offers image de-identification and storage via their research image management system

Maureen Ainslie, MS, RT(R) (MR)
919 684 7875 maureen.ainslie@duke.edu


Genotyping & Sequencing: This lab offers a variety of experimental platforms to facilitate genomics research, including genotyping, DNAre-sequencing, gene expression, copy number variation experiments of all sizes, DNAmethylation profiling, and DNA/RNA quantification and quality analysis

Karen Abramson, MPH MPH919.684.0704 karen.abramson@duke.edu


Good Manufacturing Practice (GMP) Processing Suites: These suites enable the development of cell-based products and molecular therapeutics in a specialized, multi-purpose facility that meets rigorous GMPstandards for production of clinical trial material.

Virginia Burns, PhD
919.668.4647
virginia.burns@duke.edu


Immune Monitoring: This is a Good Clinical Laboratory Practice (GCLP)-compliant laboratory that focuses on assessing subtle effects on the human immune system using flow cytometry, ELISpot, and ELISA assays, of particular importance in trials of vaccines, cancer immunotherapy, and auto-immune disorders.

Sara Sparks
919.681.8153
sara.sparks@duke.edu


Metabolics and Immunoassay Labs at the StedmanCenter: These labs develop new mass spectrometry-based metabolic profiling technologies and multiplex methods for assaying peptide hormones and inflammatory mediators. The Center’s faculty then applies these tools to basic and clinical research in the areas of obesity, diabetes, and cardiovascular disease.

James Bain, PhD
919 479 2320
bain0009@mc.duke.edu



Optical Molecular Imaging: This shared resource emphasizes in vivo optical imaging and spectroscopy of cancer in animal models. The Duke Comprehensive Cancer Center (DCCC) provides the following services: hand-held optical spectroscopy, window chamber services and the IVIS 100 (routine luciferase imaging),optical spectroscopy drug delivery, and other physiologic indicators, as well as extrinsic fluorescent probes or fluorescent proteins via a fiber optic probe

Greg Palmer, PhD
919.613.5053
greg.palmer@duke.edu




Proteomics: This facility provides protein characterization resources, as well as capabilities for mass spectrometry-based proteomics for protein identification and protein quantitation. For qualitative identifications and biomarker discovery experiments, the laboratory is equipped with four high resolution accurate mass LC/MS/MS system.






M. Arthur Moseley, PhD 919.684.4456
Arthur.moseley@duke.edu

OR

J. Will Thompson, PhD
919.684.5454 will.thompson@duke.edu



Additional services may be added at a later date.

Online application submission: https://webgrants.dtmi.duke.edu

Proposals will be accepted on a continual basis with, at minimum, quarterly review.

For more information contact:

Melissa Hall, Project Leader
Duke Translational Research Institute
919.668.8154
melissa.hall@duke.edu


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