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Research Emphasis and Experience

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Areas of research emphasis include:

  • Phase I through IV Evaluation
  • Vaccine Utilization

Vaccine research has included clinical evaluations in all age groups (infants to elderly). Specific vaccines include:

  • Bacterial
  • Viral
  • Combination
  • Novel Delivery Systems

Over 3,500 subjects have been enrolled in over 60 completed trials since 1980.

Number of Clinical Trials Completed

1980-1989

n=6

1990-1999

n=27

2000-present

n=27

Recent Duke Studies Leading to Changes in Vaccine Policy

  • Tdap and HPV vaccines for adolescents
  • Hepatitis A and combination MMRV vaccines for toddlers
  • Rotavirus vaccine for infants
  • Licensure of another inactivated flu vaccine product to enhance vaccine supply
  • Change in recommendations for dosing of influenza vaccine in childhood

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