Geoffrey Ginsburg, MD, PhD
DTRI -Omics Cores
Director, Center for Genomic Medicine
Institute for Genome Sciences and Policy
Professor of Medicine and Pathology

In 2004 Dr. Ginsburg joined Duke University to develop Duke’s strategy and programs in genomic medicine – programs aimed at the translation of genetic and genomic information from the laboratory to the clinic in order to improve the health of the individual patient and the health and economic outcomes for health systems.

Prior to joining Duke, Dr. Ginsburg was the Senior Program Director for Cardiovascular Disease at Millennium Pharmaceuticals, Inc., and subsequently was appointed Vice President of Molecular and Personalized Medicine where he was responsible for developing biomarkers for disease, pharmacogenomic strategies for therapeutics and their implementation in the drug development process. From 1990-1997, Dr. Ginsburg was a faculty member of Harvard Medical School where he was Director of Preventive Cardiology and led a laboratory in applied genetics and molecular biology in cardiovascular disease.

Dr. Ginsburg is a founding member of the Personalized Medicine Coalition and an Associate Editor for the Journal of the American College of Cardiology. He has been an international expert panel member for Genome Canada and was recently appointed to the Secretary of Veterans Affairs Advisory Council on Genomic Medicine.

Michael A. Hauser, PhD
DTRI -Omics Core
Associate Professor in Medicine
Associate Research Professor of Biostatistics and Bioinformatics
Associate Research Professor in Molecular Genetics and Microbiology
Associate Professor in Ophthalmology
Director of the Center for Human Genetics DNA Bank

Dr. Hauser's primary interest is in ocular genetics. He has used genomic linkage analysis to identify multiple linkage peaks in primary open angle glaucoma (POAG) and age related macular degeneration (AMD), and is using a combination of approaches to identify susceptibility genes with these linkage regions. Dr. Hauser also has an extensive research interest in muscular dystrophy. He has identified mutations in the myotilin gene as the cause of limb girdle muscular dystrophy 1A (LGMD1A), and constructed mouse models that recapitulate many of the pathological features of human LGMD1A. Analysis of 11 additional muscular dystrophy families is currently underway. Dr. Hauser also has an interest in the genetic etiology of Parkinson disease, post-tramatic stress disorder in US veterans, amylotrophic lateral sclerosis, and non-alcoholic fatty liver disease.

Art Moseley, PhD
DTRI -Omics Core
Director of Duke Proteomics Core Facility
Duke Institute for Genome Sciences and Policy (IGSP)

As Director of the Duke Proteomics Core Facility, Dr. Moseley is responsible for developing mass spectrometry-based proteomic technologies for preclinical and clinical projects.

Dr. Moseley received his doctorate in Analytical Chemistry from UNC – Chapel Hill and received his masters’ degree in Physical Chemistry from NC State University. With nearly 30 years of experience in research and scientific leadership, Moseley has led transnational forums on successfully delivering proteomics project portfolios, managed a transnational team, and oversaw the acquisition and management of a large-scale mass spectrometry proteomics infrastructure.

Since 1997, Moseley has been a co-instructor of a two-day course at the National Conference of the American Society for Mass Spectrometry. He was a member of the Washington University Mass Spectrometry Resource Advisory Review Committee and is also a member of the American Chemical Society and the Triangle Mass Spectrometry Discussion Group. He has written more than 40 peer-reviewed papers.

Christopher B. Newgard, PhD
DTRI -Omics Core
Director, Sarah W. Stedman Nutrition and Metabolism Center
W. David and Sarah W. Stedman Distinguished Professor
Departments of Pharmacology and Cancer Biology, Biochemistry, and Medicine

Dr. Newgard earned his Bachelor of Sciences degree at Duke University in 1978, his Ph.D. in Biochemistry at the University of Texas Southwestern Medical Center in Dallas in 1984, and performed a postdoctoral fellowship at the University of California at San Francisco from 1984-1987.

Prior to coming to Duke in 2002, Dr. Newgard was the Gifford O. Touchstone Jr. and Randolph G. Touchstone Distinguished Professor, Department of Biochemistry and the Co-Director of the Touchstone Diabetes Center at the University of Texas Southwestern Medical Center, Dallas.

Dr. Newgard's research focuses on application of an interdisciplinary approach for understanding of diabetes and obesity mechanisms involving gene discovery, metabolic engineering, and comprehensive tools of metabolic analysis ("metabolomics").

Diane Uzarski, MPH, RN
DTRI Project Leader, -Omics Core
ph: (919) 668-8595
e-mail at diane.uzarski@duke.edu

In her role as Project Leader at the DTMI, Uzarski provides facilitation and management of the ‘Omics’ core projects associated with the M.U.R.D.O.C.K. Study on the North Carolina Research Campus in Kannapolis, NC. Two key areas of responsibility are driving the DTMI-LabCorp Biorepository partnership in Kannapolis, and implementing of research strategies essential to Horizon 1 and 1.5 of the M.U.R.D.O.C.K. Study.

Prior to her role with the DTMI, Uzarski developed and expanded infrastructure to support clinical research trials and a large biorepository with Dr. John McHutchison at the Duke Clinical Research Institute. In addition, she functioned as the DCRI administrative representative to the Duke GI Research Steering Committee. Uzarski developed a research protocol feasibility blueprint, and transformed the committee into an authoritative clearinghouse for GI clinical research projects.

Uzarski has a healthcare career spanning over 25 years, including business development and health services planning, legal consulting, health services marketing, injury prevention policy planning, and emergency and critical care nursing. She served for six years on the San Francisco Tenderloin YMCA Board of Directors, as the board vice chair and the annual campaign chair.

Uzarski received a Master of Public Health degree from University of California, Berkeley in 1993, where she was a Federal Nurse Traineeship Grant Recipient. She graduated from Iona College with a BS in Health Care Administration, and earned a nursing diploma from the Bridgeport Hospital School of Nursing.